Baricitinib-d5 is a deuterium-labeled derivative of Baricitinib, a selective inhibitor of Janus kinase 1 (JAK1) and Janus kinase 2 (JAK2) with IC50 values of 5.9 nM and 5.7 nM, respectively. This stable isotope analog is useful for various research applications, including pharmacokinetic studies and metabolic tracing. Its unique labeling enables in-depth analysis of JAK-mediated signaling pathways and therapeutic efficacy in disease models.
Baricitinib-d5 is a deuterium-labeled derivative of Baricitinib, a selective inhibitor of Janus kinase 1 (JAK1) and Janus kinase 2 (JAK2) with IC50 values of 5.9 nM and 5.7 nM, respectively. This stable isotope analog is useful for various research applications, including pharmacokinetic studies and metabolic tracing. Its unique labeling enables in-depth analysis of JAK-mediated signaling pathways and therapeutic efficacy in disease models.
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