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Baricitinib phosphate

JAK inhibitor

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Catalog No. A15014

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Baricitinib phosphate 10mg A15014-10
Baricitinib phosphate 25mg A15014-25
Baricitinib phosphate 50mg A15014-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Baricitinib phosphate is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.

Baricitinib phosphate

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Chemical Information

Catalog Num A15014
Actions Inhibitor
M. Wt 469.41
Formula C16H20N7O6PS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1187595-84-1
Synonyms INCB 028050, LY 3009104, INCB028050, LY3009104, LY-3009104, INCB-028050

Biological Activity

Baricitinib phosphate is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, ~70 and ~10-fold selective versus JAK3 and Tyk2, no inhibition to c-Met and Chk2.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.3 mL 106.52 mL 213.03mL
0.5 mM 4.26 mL 21.3 mL 42.61 mL
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL

*The above data is based on the productmolecular weight 469.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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