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Baricitinib (LY3009104)


JAK Inhibitor

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Catalog No. A11329

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Baricitinib 5mg A11329-5

Regular Price: $60.00

Special Price: $54.00

Baricitinib 10mg A11329-10

Regular Price: $70.00

Special Price: $63.00

Baricitinib 25mg A11329-25

Regular Price: $90.00

Special Price: $81.00

Baricitinib 50mg A11329-50

Regular Price: $120.00

Special Price: $108.00

Baricitinib (LY3009104) 10mM * 1mL in DMSO A11329-10mM-D

Regular Price: $60.00

Special Price: $54.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Baricitinib, also known as INCB028050 or LY3009104, is a selective orally bioavailable JAK1/JAK2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK2 (5.7 nM).

Baricitinib (LY3009104)

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Chemical Information

Catalog Num A11329
Actions Inhibitor
M. Wt 371.4
Formula C16H17N7O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1187594-09-7
Synonyms INCB28050, LY3009104

Biological Activity

Baricitinib, also known as INCB028050 or LY3009104, is a selective orally bioavailable JAK1/JAK2 inhibitor with nanomolar potency against JAK1 (5.9 nM) and JAK2 (5.7 nM).
Target Value
JAK2IC50: 5.7nM
JAK1IC50: 5.9nM
TYK2IC50: 53nM
JAK3IC50: >400nM
Chk2IC50: >1μM
c-MetIC50: >10μM


Solubility (25°C) * In vitro DMSO 74 mg/mL (199.23 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.93 mL 134.63 mL 269.25mL
0.5 mM 5.39 mL 26.93 mL 53.85 mL
1 mM 2.69 mL 13.46 mL 26.93 mL
5 mM 0.54 mL 2.69 mL 5.39 mL

*The above data is based on the productmolecular weight 371.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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