Fig. 1 · Structure
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BAS00602705
E-cadherin Inhibitor
BAS00602705 is an E-cadherin inhibitor that disrupts the trans-interactions of E-cadherin molecules within junctional complexes, thereby impeding cellular adhesion without permanently affecting E-cadherin expression. This compound significantly inhibits invadopodia formation in pancreatic cancer cells, making it a valuable tool for investigating anti-invasive therapeutic strategies. BAS00602705 is particularly relevant for research involving cancers with dysregulated E-cadherin-mediated invadopodia activity, such as pancreatic ductal adenocarcinoma (PDAC).
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 317321-89-4 |
| Applications | E-cadherin Inhibitor |
| Formula | C25H22BrN3O3 |
| Molecular Weight | 492.36 |
| SMILES | O=C(NC(CC1=CNC2=C1C=CC=C2)C(NC3=CC=C(C=C3)Br)=O)OCC4=CC=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.