Documents & Downloads

Basivarsen

Myotonic Dystrophy

Basivarsen (DYNE-101 oligomer) is an antisense oligonucleotide designed to target mutant DMPK RNA for RNase H-mediated degradation, facilitating the correction of splicing defects. Its primary application is in the research of myotonic dystrophy type 1 (DM1), providing a valuable tool for investigating disease mechanisms and potential therapeutic approaches. This compound enhances the understanding of RNA-mediated pathogenesis and aids in the development of targeted treatments for DM1.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
CAS Number	3028750-61-7
Applications	Myotonic Dystrophy
Molecular Weight	6726.91
Synonyms	DYNE-101 oligomer

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.