Fig. 1 · Structure

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BAY-069

BCAT1/2 Inhibitor

BAY-069 is a selective inhibitor of branched-chain amino acid transaminases 1 (BCAT1) and BCAT2, exhibiting IC50 values of 31 nM and 153 nM, respectively. This compound serves as a valuable chemical probe in biochemical research, facilitating the investigation of branched-chain amino acid metabolism. BAY-069 is particularly relevant for studies focused on anticancer mechanisms, offering insights into metabolic reprogramming in tumors.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2639638-66-5
Applications BCAT1/2 Inhibitor
Formula C22H14ClF3N2O3
Molecular Weight 446.81
SMILES
CC(C=CC=C1)=C1OC2=C(Cl)C3=C(C=CC=C3)C(N4C(NC(C(F)(F)F)=CC4=O)=O)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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