BAY-1112054 hydrochloride is a potent inhibitor of PTEFb/CDK9, demonstrating high selectivity within the cyclin-dependent kinase family. This compound exhibits significant antiproliferative activity against various cancer cell lines, including HeLa and MOLM-13. BAY-1112054 hydrochloride is characterized by good metabolic stability and effectively suppresses tumor growth in mouse xenograft models while maintaining a favorable toxicity profile. Its mechanism and efficacy make it a valuable tool for cancer research applications.
BAY-1112054 hydrochloride is a potent inhibitor of PTEFb/CDK9, demonstrating high selectivity within the cyclin-dependent kinase family. This compound exhibits significant antiproliferative activity against various cancer cell lines, including HeLa and MOLM-13. BAY-1112054 hydrochloride is characterized by good metabolic stability and effectively suppresses tumor growth in mouse xenograft models while maintaining a favorable toxicity profile. Its mechanism and efficacy make it a valuable tool for cancer research applications.
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