Fig. 1 · Structure

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BAY 1135626

Anticancer Agent

BAY 1135626 is an anticancer agent primarily utilized in the synthesis of BAY 1129980. This compound serves as the basis for an Auristatin-based antibody-drug conjugate targeting C4.4A (LYPD3), specifically applied in studies focused on non-small cell lung cancer (NSCLC). Its role in advancing ADC research underscores its significance in the development of targeted cancer therapies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1404071-37-9
Applications Anticancer Agent
Formula C55H86N10O11
Molecular Weight 1063.33
SMILES
CO[C@@H]([C@@]1([H])N(CCC1)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)CCCC(NNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)=O)=O)[C@@H](C)C(N[C@H](C(N)=O)CC3=CNC4=CC=CC=C34)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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