BAY 1214784 is a potent and selective antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R), classified as a spiroindoline derivative. This compound effectively reduces plasma luteinizing hormone levels by up to 49%, demonstrating low pharmacokinetic variability and good tolerability in biological assays. BAY 1214784 holds promise for research applications related to uterine fibroids, providing a valuable tool for studies in reproductive health and hormone regulation.
BAY 1214784 is a potent and selective antagonist of the human gonadotropin-releasing hormone receptor (hGnRH-R), classified as a spiroindoline derivative. This compound effectively reduces plasma luteinizing hormone levels by up to 49%, demonstrating low pharmacokinetic variability and good tolerability in biological assays. BAY 1214784 holds promise for research applications related to uterine fibroids, providing a valuable tool for studies in reproductive health and hormone regulation.
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