BAY-1436032

Catalog No.: A17059

mIDH1 inhibitor

BAY-1436032

BAY-1436032 Chemical Structure

CAS NO. 1803274-65-8

BAY-1436032 is a potent, selective and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1).

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$220.00
50 mg
$820.00
100 mg
$1,520.00
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Biological Activity

BAY-1436032 is a potent, selective and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1).
In vitro DMSO 85 mg/mL (173.63 mM)
Water Insoluble
Ethanol 85 mg/mL (173.63 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.43 mL 102.14 mL 204.27 mL
0.5 mM 4.09 mL 20.43 mL 40.85 mL
1 mM 2.04 mL 10.21 mL 20.43 mL
5 mM 0.41 mL 2.04 mL 4.09 mL

*The above data is based on the productmolecular weight 489.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17059
Actions Inhibitor
CAS No. 1803274-65-8
Formula C26H30F3N3O3
M. Wt 489.54
Solubility DMSO
Purity >98%
Synonyms BAY1436032, BAY 1436032
SMILES O=C(O)CCC1=CC=C2N([[email protected]]3CC(C)(C)C[[email protected]@H](C)C3)C(NC4=CC=C(OC(F)(F)F)C=C4)=NC2=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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