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BAY-293 is a potent, cell-active SOS1 inhibitor that disrupts the KRAS-SOS1 interaction with IC50 of 21 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.29 mL | 111.46 mL | 222.92 mL |
| 0.5 mM | 4.46 mL | 22.29 mL | 44.58 mL |
| 1 mM | 2.23 mL | 11.15 mL | 22.29 mL |
| 5 mM | 0.45 mL | 2.23 mL | 4.46 mL |
*The above data is based on the productmolecular weight 448.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18319 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 448.59 |
| Formula | C25H28N4O2S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2244904-70-7 |
| Synonyms | BAY293, BAY-293 |
| SMILES | CNCC1=C(C=CC=C1)C1=CSC(=C1)[[email protected]@H](C)NC1=NC(C)=NC2=C1C=C(OC)C(OC)=C2 |
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