BAY 36-7620 is a potent noncompetitive antagonist of the metabotropic glutamate receptor 1 (mGlu1), with an IC50 of 0.16 μM and exhibiting inverse agonist activity. This compound has demonstrated significant antitumor effects by inhibiting mGlu1 receptor activity, leading to reduced AKT phosphorylation in A549 tumor models and improved survival in mice with tumors. Additionally, BAY 36-7620 provides neuroprotective effects in acute subdural hematoma models. It serves as a valuable tool in research focused on non-small cell lung cancer and breast cancer.
BAY 36-7620 is a potent noncompetitive antagonist of the metabotropic glutamate receptor 1 (mGlu1), with an IC50 of 0.16 μM and exhibiting inverse agonist activity. This compound has demonstrated significant antitumor effects by inhibiting mGlu1 receptor activity, leading to reduced AKT phosphorylation in A549 tumor models and improved survival in mice with tumors. Additionally, BAY 36-7620 provides neuroprotective effects in acute subdural hematoma models. It serves as a valuable tool in research focused on non-small cell lung cancer and breast cancer.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
