BAY-678

Catalog No.: A16866

HNE inhibitor

BAY-678

BAY-678 Chemical Structure

CAS NO. 675103-36-3

BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
50 mg
$400.00
100 mg
$720.00
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Biological Activity

BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.98 mL 124.89 mL 249.78 mL
0.5 mM 5 mL 24.98 mL 49.96 mL
1 mM 2.5 mL 12.49 mL 24.98 mL
5 mM 0.5 mL 2.5 mL 5 mL

*The above data is based on the productmolecular weight 400.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16866
Actions Inhibitor
M. Wt 400.35
Formula C20H15F3N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 675103-36-3
Synonyms BAY 678, BAY678
SMILES N#CC1=NC=C([[email protected]](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1

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