BAY 87-2243

Catalog No.: A12978
HIF inhibitor
BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I.
Grouped product items
Product Name Price Stock Qty
BAY 87-2243 5mg
$70.00
In stock
BAY 87-2243 10mg
$120.00
In stock
BAY 87-2243 25mg
$240.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I.
Targets
Target Value
Product Information
Catalog Num A12978
Formula C26H26F3N7O2
Molecular Weight 525.53
CAS Number 1227158-85-1
SMILES CC1=CC(=NN1CC2=CC(=NC=C2)N3CCN(CC3)C4CC4)C5=NC(=NO5)C6=CC=C(C=C6)OC(F)(F)F
Synonyms BAY-87-2243
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO Warmed: 33 mg/mL (62.79 mM)
Water Insoluble
Ethanol Warmed: 8 mg/mL (15.22 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.03 mL 95.14 mL 190.28 mL
0.5 mM 3.81 mL 19.03 mL 38.06 mL
1 mM 1.9 mL 9.51 mL 19.03 mL
5 mM 0.38 mL 1.9 mL 3.81 mL
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