BAY 87-2243

Catalog No.: A12978

HIF inhibitor

BAY 87-2243

BAY 87-2243 Chemical Structure

CAS NO. 1227158-85-1

BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $70.00

Special Price $63.00

10 mg

Regular Price: $120.00

Special Price $108.00

25 mg

Regular Price: $240.00

Special Price $216.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I.
Targets
HIF-1 (Cell-free assay)
In vitro DMSO <1 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol 8 mg/mL heating (15.22 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.03 mL 95.14 mL 190.28 mL
0.5 mM 3.81 mL 19.03 mL 38.06 mL
1 mM 1.9 mL 9.51 mL 19.03 mL
5 mM 0.38 mL 1.9 mL 3.81 mL

*The above data is based on the productmolecular weight 525.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A12978
Actions Inhibitor
M. Wt 525.53
Formula C26H26F3N7O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1227158-85-1
Synonyms BAY-87-2243
SMILES CC1=CC(=NN1CC2=CC(=NC=C2)N3CCN(CC3)C4CC4)C5=NC(=NO5)C6=CC=C(C=C6)OC(F)(F)F

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