BAY 87-2243

Catalog No.: A12978

HIF inhibitor

BAY 87-2243

BAY 87-2243 Chemical Structure

CAS NO. 1227158-85-1

BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I.

Availability: In stock

Package Price Qty
5 mg
$70.00
10 mg
$120.00
25 mg
$240.00
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Biological Activity

BAY 87-2243, a highly potent and selective inhibitor of hypoxia-induced gene activation has antitumor activities by inhibition of mitochondrial complex I.
Targets
HIF-1 (Cell-free assay)
In vitro DMSO Warmed: 33 mg/mL (62.79 mM)
Water Warmed: 8 mg/mL (15.22 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.03 mL 95.14 mL 190.28 mL
0.5 mM 3.81 mL 19.03 mL 38.06 mL
1 mM 1.9 mL 9.51 mL 19.03 mL
5 mM 0.38 mL 1.9 mL 3.81 mL

*The above data is based on the productmolecular weight 525.53. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12978
Actions Inhibitor
CAS No. 1227158-85-1
Formula C26H26F3N7O2
M. Wt 525.53
Solubility DMSO
Purity >98%
Synonyms BAY-87-2243
SMILES CC1=CC(=NN1CC2=CC(=NC=C2)N3CCN(CC3)C4CC4)C5=NC(=NO5)C6=CC=C(C=C6)OC(F)(F)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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