BAY1217389

Catalog No.: A21595

MPS1 kinase inhibitor

BAY1217389

BAY1217389 Chemical Structure

CAS NO. 1554458-53-5

BAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.

Availability: In stock

Package Price Qty
2 mg
$54.00
5 mg
$108.00
10 mg
$210.00
50 mg
$618.00
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Biological Activity

BAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.
In vitro DMSO 92 mg/mL (163.84 mM)
Water Insoluble
Ethanol Warmed: 3 mg/mL (5.34 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.81 mL 89.05 mL 178.09 mL
0.5 mM 3.56 mL 17.81 mL 35.62 mL
1 mM 1.78 mL 8.9 mL 17.81 mL
5 mM 0.36 mL 1.78 mL 3.56 mL

*The above data is based on the productmolecular weight 561.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21595
Actions Inhibitor
CAS No. 1554458-53-5
Formula C27H24F5N5O3
M. Wt 561.5
Purity >98%
Synonyms BAY 1217389, BAY-1217389
SMILES O=C(NC1CC1)C2=CC=C(C3=CN=C4C(NCCC(F)(F)F)=CC(OC5=CC=C(OC)C(F)=C5F)=NN43)C=C2C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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