Bazlitoran sodium

Catalog No.: A35449
TLR antagonists
Bazlitoran sodium is an oligonucleotide that serves as an antagonist of Toll-like receptors TLR7, TLR8, and TLR9. It exhibits potential immunomodulatory effects by inhibiting the activation of these receptors, which play crucial roles in the innate immune response. This compound has applications in research focusing on autoimmune disorders, viral infections, and related inflammatory conditions.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBazlitoran sodium is an oligonucleotide that serves as an antagonist of Toll-like receptors TLR7, TLR8, and TLR9. It exhibits potential immunomodulatory effects by inhibiting the activation of these receptors, which play crucial roles in the innate immune response. This compound has applications in research focusing on autoimmune disorders, viral infections, and related inflammatory conditions.
Product Information
Catalog NumA35449
FormulaC179H225N52Na17O101P17S17
Molecular Weight6183.47
CAS Number1613607-40-1
SMILES[Bazlitoran (sodium)]
SynonymsIMO-8400 sodium
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