Bazlitoran

Catalog No.: A35409
TLR antagonists
Bazlitoran is a potent antagonist of Toll-like receptors 7, 8, and 9 (TLR7, TLR8, and TLR9). This oligonucleotide modulates immune responses by inhibiting TLR-mediated signaling pathways, making it an essential tool for studying the role of these receptors in various inflammatory diseases and autoimmune conditions. Research applications include the exploration of therapeutic strategies targeting TLR signaling in infectious diseases and cancer.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBazlitoran is a potent antagonist of Toll-like receptors 7, 8, and 9 (TLR7, TLR8, and TLR9). This oligonucleotide modulates immune responses by inhibiting TLR-mediated signaling pathways, making it an essential tool for studying the role of these receptors in various inflammatory diseases and autoimmune conditions. Research applications include the exploration of therapeutic strategies targeting TLR signaling in infectious diseases and cancer.
Product Information
Catalog NumA35409
FormulaC179H233N52O101P17S17
Molecular Weight5800.70
CAS Number1378549-07-5
SMILES[Bazlitoran]
SynonymsIMO-8400
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