Fig. 1 · Structure
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BB 0305179
Anti-prion Agent
BB 0305179 is a potent anti-prion agent that exhibits an IC50 of 4.7 μM against specific PrP mutants with deletions in the hydrophobic domain. This compound not only inhibits the toxicity associated with prion diseases but also serves as a click chemistry reagent, containing an alkyne group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its unique properties make BB 0305179 suitable for research applications in prion biology and related studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2512200-83-6 |
| Applications | Anti-prion Agent |
| Formula | C21H29NO |
| Molecular Weight | 311.46 |
| SMILES | O[C@]1(CCCC[C@@H]1NCC2CCCCC2)C#CC3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.