BBS-4 is a highly potent and selective inhibitor of inducible nitric oxide synthase (iNOS, NOS2) dimerization, demonstrating an IC50 of 0.49 nM. This compound is primarily utilized in research focused on cardiovascular dysfunction, notably offering protective effects in murine models of sepsis. Its selective inhibition of iNOS makes BBS-4 a valuable tool for investigating nitric oxide-related pathologies and potential therapeutic interventions.
BBS-4 is a highly potent and selective inhibitor of inducible nitric oxide synthase (iNOS, NOS2) dimerization, demonstrating an IC50 of 0.49 nM. This compound is primarily utilized in research focused on cardiovascular dysfunction, notably offering protective effects in murine models of sepsis. Its selective inhibition of iNOS makes BBS-4 a valuable tool for investigating nitric oxide-related pathologies and potential therapeutic interventions.
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