Fig. 1 · Structure
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BC-DXI-843
AIMP2-DX2 Inhibitor
BC-DXI-843 is a selective inhibitor of AIMP2-DX2, exhibiting an IC50 of 0.92 μM, with over 100-fold selectivity against AIMP2 (IC50 >100 μM) demonstrated in a luciferase assay. This compound shows potential as a therapeutic lead for targeting AIMP2-DX2 in lung cancer research. Its specificity and potency make it a valuable tool for investigating the role of AIMP2-DX2 in cellular processes and cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2421117-98-6 |
| Applications | AIMP2-DX2 Inhibitor |
| Formula | C28H26N4O4S2 |
| Molecular Weight | 546.66 |
| SMILES | COC(C=C1)=CC=C1C2=CSC(NC([C@@H](NS(C3=CC=C(C)C=C3)(=O)=O)CC4=CNC5=C4C=CC=C5)=O)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.