Fig. 1 · Structure
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BC1618
Fbxo48 Inhibitor
BC1618 is a potent inhibitor of Fbxo48, functioning by blocking its degradation of activated pAMPKα, thereby stimulating AMPK-dependent signaling pathways. This compound promotes mitochondrial fission and enhances autophagy while improving hepatic insulin sensitivity. BC1618 is valuable for research on metabolic disorders and cellular energy regulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2222094-18-8 |
| Applications | Fbxo48 Inhibitor |
| Formula | C24H24F3NO2 |
| Molecular Weight | 415.45 |
| SMILES | OC(COC1=CC=C(C(F)(F)F)C=C1)CN(CC2=CC=CC=C2)CC3=CC=CC=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.