Fig. 1 · Structure
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BCATc Inhibitor 2
BCAT Inhibitor
BCATc Inhibitor 2 is a selective inhibitor of branched-chain aminotransferase (BCAT), specifically targeting the cytosolic isoenzymes rBCATc and hBCATc, with IC50 values of 0.2 μM and 0.8 μM, respectively. This compound plays a crucial role in the investigation of neurodegenerative diseases by modulating metabolic pathways involving branched-chain amino acids. Additionally, it may provide insights into the therapeutic potential of BCAT inhibition in various neurological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 406191-34-2 |
| Applications | BCAT Inhibitor |
| Formula | C16H10ClF3N2O4S |
| Molecular Weight | 418.77 |
| SMILES | ClC1=CC=C2C(C=C(O2)C(NNS(C3=C(C=CC=C3)C(F)(F)F)(=O)=O)=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.