BCL6 ligand-8

Catalog No.: A64142
BCL6 Ligand
BCL6 ligand-8 is a bifunctional linker designed to target the BCL6 protein for degradation via the PROTAC (Proteolysis Targeting Chimeras) mechanism. This compound plays a crucial role in the synthesis of PROTACs, including the effective BCL6-760, known for its anti-tumor properties. BCL6 ligand-8 is primarily utilized in cancer research to explore therapeutic strategies involving protein degradation pathways.
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5mg
10mg
50mg
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionBCL6 ligand-8 is a bifunctional linker designed to target the BCL6 protein for degradation via the PROTAC (Proteolysis Targeting Chimeras) mechanism. This compound plays a crucial role in the synthesis of PROTACs, including the effective BCL6-760, known for its anti-tumor properties. BCL6 ligand-8 is primarily utilized in cancer research to explore therapeutic strategies involving protein degradation pathways.
Product Information
Catalog NumA64142
FormulaC17H19ClFN5O2
Molecular Weight379.82
CAS Number3084697-86-6
SMILESCN(C(N(C1=C2)CCC(C)(O)C)=O)C1=CC=C2NC(N=C(F)N=C3)=C3Cl
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