Fig. 1 · Structure
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BDM14471
PfAM1 Inhibitor
BDM14471 is a selective inhibitor of hydroxamate aminopeptidase M1 (PfAM1), exhibiting an IC50 value of 6 nM. This compound demonstrates potent inhibition of PfAM1, making it a valuable tool for studying Plasmodium falciparum biology and potential therapeutic interventions against malaria. Its high specificity allows for targeted research applications in enzymology and drug discovery related to malaria treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 934618-96-9 |
| Applications | PfAM1 Inhibitor |
| Formula | C17H15FN2O3 |
| Molecular Weight | 314.31 |
| SMILES | O=C(/C(C(NO)=O)=C/C1=CC=CC=C1)NCC2=CC=C(C=C2)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.