Fig. 1 · Structure
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Beauvericin
Anticancer Fungal Mycotoxin
Beauvericin is a cyclohexapeptide derived from the Fusarium species, primarily targeting anticancer pathways. It exhibits significant anticancer activity by inducing apoptosis and inhibiting the PI3K/AKT signaling pathway, thereby suppressing the growth of hepatocellular carcinoma (HCC). Additionally, Beauvericin demonstrates immunomodulatory effects by inhibiting lymphocyte proliferation and disrupting the differentiation of human monocytes into macrophages, making it a valuable reagent for studies in cancer and immune response research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 26048-05-5 |
| Applications | Anticancer Fungal Mycotoxin |
| Formula | C45H57N3O9 |
| Molecular Weight | 783.95 |
| SMILES | CN([C@H](C(O[C@](C(N([C@H](C(O[C@@H]1C(C)C)=O)CC2=CC=CC=C2)C)=O)([H])C(C)C)=O)CC3=CC=CC=C3)C([C@H](OC([C@@H](N(C1=O)C)CC4=CC=CC=C4)=O)C(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.