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Belcesiran

A1AT inhibitor

Belcesiran is a small interfering RNA (siRNA) that targets and inhibits alpha-1 antitrypsin (A1AT) production. By downregulating A1AT synthesis in the liver, it promotes the understanding of A1AT-related conditions and potential therapeutic interventions. This compound is primarily utilized in research focused on liver function and A1AT deficiency disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2375562-54-0
Applications	A1AT inhibitor
Formula	C₆₆₆H₈₇₇O₄₁₇N₂₃₁F₁₅P₅₇S₆
Molecular Weight	21033.20
Synonyms	DCR-S1459

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.