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Beloranib hemioxalate

MetAP2 Inhibitor

Beloranib hemioxalate is a potent inhibitor of methionine aminopetidase-2 (MetAP2), a key enzyme involved in protein synthesis and signaling pathways. This compound has demonstrated significant biological activity by reducing food intake, body weight, and fat mass, while also decreasing adipocyte size. Beloranib hemioxalate is widely utilized in obesity research, contributing to a better understanding of anti-obesity mechanisms and potential therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	529511-79-3
Applications	MetAP2 Inhibitor
Formula	C₂₉H₄₁NO₆.1/2C₂H₂O₄
Molecular Weight	1089.32
Synonyms	ZGN-440 hemioxalate; ZGN-433 hemioxalate; CDK732 hemioxalate
SMILES	C[C@]1([C@H](O1)C/C=C(C)\C)[C@]2([H])[C@]3(CC[C@H]([C@H]2OC)OC(/C=C/C4=CC=C(C=C4)OCCN(C)C)=O)CO3.O=C(O)C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.