Fig. 1 · Structure
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Benzyl-α-GalNAc
O-Glycosylation Inhibitor
Benzyl-α-GalNAc is a potent inhibitor of O-glycosylation, primarily targeting glycosylation processes involved in cellular signaling. It has been shown to effectively inhibit the proliferation and activation of LX-2 cells, as well as suppress the expression of collagens I and III, making it valuable for research related to liver fibrosis. Additionally, Benzyl-α-GalNAc can enhance the anti-tumor efficacy of 5-Fluorouracil, particularly in pancreatic cancer, by mitigating O-glycosylation effects.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3554-93-6 |
| Applications | O-Glycosylation Inhibitor |
| Formula | C15H21NO6 |
| Molecular Weight | 311.33 |
| SMILES | O[C@@H]([C@H]([C@@H](CO)O1)O)[C@@H](NC(C)=O)[C@H]1OCC2=CC=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.