Fig. 1 · Structure
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Benzylacyclouridine
Uridine Phosphorylase Inhibitor
Benzylacyclouridine is a potent and selective inhibitor of uridine phosphorylase, a key enzyme in the catabolism of uridine. By targeting uridine phosphorylase, it effectively inhibits the enzymatic activity of UPP1 and UPP2, which may help to modulate the cytotoxicity of 5-fluorouracil (5-FU) and its derivatives. This compound is valuable for research into cancer therapy and metabolic pathways involving uridine.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 82857-69-0 |
| Applications | Uridine Phosphorylase Inhibitor |
| Formula | C14H16N2O4 |
| Molecular Weight | 276.29 |
| Synonyms | BAU; 5-Benzylacyclouridine |
| SMILES | OCCOCN(C(NC1=O)=O)C=C1CC2=CC=CC=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.