Fig. 1 · Structure
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BET-BAY 002 (S enantiomer)
Epigenetic Reader Domain
BET-BAY 002 (S enantiomer) is a selective inhibitor targeting the Bromodomain and Extra-Terminal (BET) protein family, specifically within the epigenetic reader domain. This compound exhibits potent activity in modulating gene expression by disrupting BET protein interactions with acetylated lysines. It is utilized in research to explore the roles of BET proteins in various biological processes, including cancer biology and inflammatory responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2070009-49-1 |
| Applications | Epigenetic Reader Domain |
| Formula | C22H18ClN5O |
| Molecular Weight | 403.86 |
| SMILES | CC1=NN=C2N1C3=CC=CC=C3C(C4=CC=C(Cl)C=C4)=C[C@@H]2CC5=NN=C(C)O5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.