Fig. 1 · Structure
Documents & Downloads
BET bromodomain inhibitor 1
Epigenetic Reader Domain Inhibitor
BET Bromodomain Inhibitor 1 is a selective inhibitor targeting bromodomain and extra-terminal (BET) proteins, specifically exhibiting an IC50 of 2.6 nM for BRD4. This compound demonstrates high affinity for BRD2, BRD3, BRD4, and BRDT, with Kd values ranging from 1.0 nM to 3.0 nM. BET Bromodomain Inhibitor 1 has shown anti-cancer activity, making it a valuable tool for research in epigenetic regulation and cancer biology.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2411226-02-1 |
| Applications | Epigenetic Reader Domain Inhibitor |
| Formula | C22H19F2N3O4S |
| Molecular Weight | 459.47 |
| SMILES | O=C1C2=C(C)C=C(C3=CC(CS(=O)(CC)=O)=CN=C3OC4=CC=C(F)C=C4F)N2C=CN1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.