Fig. 1 · Structure
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BET bromodomain inhibitor 4
Epigenetic Reader Domain Inhibitor
BET Bromodomain Inhibitor 4 is a selective inhibitor targeting the bromodomains of BET proteins, which play a crucial role in modulating gene expression through acetylation recognition. This compound demonstrates significant biological activity in disrupting the interaction between chromatin and BET proteins, influencing epigenetic regulation and transcriptional control. It is extensively utilized in research applications focused on cancer, inflammation, and other diseases where epigenetic modifications are implicated.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2407658-41-5 |
| Applications | Epigenetic Reader Domain Inhibitor |
| Formula | C27H31FN8O2 |
| Molecular Weight | 518.59 |
| SMILES | CC(N=NN1C)=C1C2=CN=C(C3=C2)C(N(N=C4C(C)(O)C)C)=C4N3[C@@H](C5CCOCC5)C6=C(C=CC=N6)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.