Fig. 1 · Structure
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Betamethasone 17-Propionate
Biochemical Assay Reagent
Betamethasone 17-Propionate is a corticosteroid with anti-inflammatory properties, primarily acting on immune cell infiltration in ocular tissues. It has been shown to inhibit cell infiltration into the aqueous humor in endotoxin-induced uveitis in preclinical models. This compound serves as a valuable tool for studying inflammatory processes and cytokine release. In in vitro assays, it exhibits a lesser inhibitory effect on IL-8 release from rat peritoneal exudate cells compared to its structurally related counterparts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 5534-13-4 |
| Applications | Biochemical Assay Reagent |
| Formula | C25H33FO6 |
| Molecular Weight | 448.52 |
| SMILES | CCC(O[C@]1([C@@]2([C@@]([C@@]3([H])[C@]([C@H](C2)O)([C@@]4(C(CC3)=CC(C=C4)=O)C)F)([H])C[C@@H]1C)C)C(CO)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.