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Betamethasone succinate

Nano Formulation

Betamethasone succinate is a nano-formulation designed for effective delivery across the blood-brain barrier. This formulation encapsulates Betamethasone semi-succinate in PEG-liposomes, utilizing the enhanced permeation and retention properties of liposomes. Betamethasone succinate exhibits significant anti-inflammatory activity by inhibiting the secretion of pro-inflammatory cytokines such as TNF-α and IL-6, while preserving TGF-β levels. This compound is suitable for research applications related to arthritis and cerebral malaria, providing a targeted approach for inflammatory conditions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	27297-42-3
Applications	Nano Formulation
Formula	C₂₆H₃₃FO₈
Molecular Weight	492.53
Synonyms	NSSL-BMS
SMILES	C[C@@]12[C@](C[C@@H]([C@]2(O)C(COC(CCC(O)=O)=O)=O)C)([H])[C@@]3([H])[C@]([C@H](C1)O)([C@@]4(C(CC3)=CC(C=C4)=O)C)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.