Fig. 1 · Structure
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Bexarotene-13C4
Stable Isotope
Bexarotene-13C4 is a stable isotope-labeled analog of Bexarotene, a high-affinity selective agonist of retinoid X receptors (RXR). It demonstrates potent activity with EC50 values of 33, 24, and 25 nM for RXRα, RXRβ, and RXRγ, respectively, while exhibiting minimal affinity for RAR receptors (EC50 >10000 nM). This compound is primarily utilized in research related to cutaneous T-cell lymphoma, enhancing studies involving RXR-mediated signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1185030-01-6 |
| Applications | Stable Isotope |
| Formula | C2013C4H28O2 |
| Molecular Weight | 352.45 |
| Synonyms | LGD1069-13C4 |
| SMILES | C=C(C1=CC2=C(C([13CH3])(CCC2([13CH3])[13CH3])[13CH3])C=C1C)C3=CC=C(C=C3)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.