Fig. 1 · Structure
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BFF-816
KAT II Inhibitor
BFF-816 is an orally active inhibitor of kynurenine aminotransferase II (KAT II). This compound selectively modulates the kynurenine pathway, which plays a significant role in neurobiology and has implications in neurodegenerative diseases. BFF-816 is utilized in research focusing on the biological effects of kynurenine and its metabolites on neuronal function and inflammation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2008006-36-6 |
| Applications | KAT II Inhibitor |
| Formula | C21H16N2O3S |
| Molecular Weight | 376.43 |
| SMILES | O=C1N2C3=C(CC1)C(C4=CC(/C=C5C(NC(S/5)=O)=O)=CC=C4)=CC=C3CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.