Biological Activity
BGB-102 is a potent multi-kinase inhibitor against EGFR, HER2, and HER4 with IC50s of 9.6 nM, 18 nM and 40.3 nM, respectively.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 21.86 mL | 109.32 mL | 218.65 mL |
0.5 mM | 4.37 mL | 21.86 mL | 43.73 mL |
1 mM | 2.19 mL | 10.93 mL | 21.86 mL |
5 mM | 0.44 mL | 2.19 mL | 4.37 mL |
*The above data is based on the productmolecular weight 457.36. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A21288 |
---|---|
Actions | Inhibitor |
M. Wt | 457.36 |
Formula | C22H25BrN4O2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 807640-87-5 |
Synonyms | JNJ-26483327 |
SMILES | CN1CCCCCOC(C(OC)=C2)=CC3=C2N=CN/C3=N\C4=CC(Br)=CC=C4C1 |
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