Fig. 1 · Structure
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BGSN3
Benzyl-Guanine Substrate
BGSN3 is a benzyl-guanine substrate targeted for use with SNAP-tag and H5 enzymes, demonstrating reasonable enzymatic activity with IC50 values of 17.8 µM and 10 µM, respectively. This compound functions as a click chemistry reagent, featuring an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, BGSN3 can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules that possess DBCO or BCN groups, making it a versatile tool for biochemical research and labeling applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Substrate |
| CAS Number | 2996069-91-9 |
| Applications | Benzyl-Guanine Substrate |
| Formula | C17H19N9O2 |
| Molecular Weight | 381.39 |
| SMILES | O=C(NCC1=CC=C(COC2=NC(N)=NC3=C2N=CN3)C=C1)CCCN=[N+]=[N-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.