Fig. 1 · Structure
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BH3I-2'
Active Compound
BH3I-2' is a Bcl-2 family inhibitor primarily designed to antagonize the activity of prosurvival members of the Bcl-2 protein family. This compound exhibits significant ability to induce apoptosis in cancer cells, making it a valuable tool in studies focused on cancer biology and therapeutic strategies targeting apoptosis pathways. Its diverse applications include investigating cell survival mechanisms and exploring potential treatments for various malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 315195-18-7 |
| Applications | Active Compound |
| Formula | C19H11Cl3INO4S |
| Molecular Weight | 582.62 |
| SMILES | O=C(C1=CC(Cl)=CC(I)=C1O)NC2=CC(S(=O)(C3=CC=C(C=C3)Cl)=O)=CC=C2Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.