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BI-1124

Name: BI-1124
Brand: Adooq Bioscience
SKU: A39882
Availability: OutOfStock

Cat. No. A39882 CAS 752237-69-7

Cathepsin S Inhibitor

BI-1124 is a selective inhibitor of cathepsin S, a cysteine protease involved in various pathological processes, including inflammation and tissue remodeling. This compound demonstrates effective ocular pharmacokinetic-pharmacodynamic properties in rabbit models following topical administration. BI-1124 is primarily utilized in research focused on age-related dry eye disease, making it a valuable tool for exploring therapeutic interventions in ocular health.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	752237-69-7
Applications	Cathepsin S Inhibitor
Formula	C₂₂H₃₉N₅O₃
Molecular Weight	421.59
SMILES	N(C([C@@H](NC(=O)N1CCOCC1)CCC(C)(C)C)=O)C2(C#N)CCN(CCC)CC2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.