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BI 1265162

ENaC Inhibitor

BI 1265162 is a potent endothelial sodium channel (ENaC) inhibitor. This compound has significant relevance in cystic fibrosis research, where modulation of sodium transport is crucial for understanding disease mechanisms and exploring therapeutic options. BI 1265162 can be utilized to investigate the physiological roles of ENaC and the impact of its inhibition on ion transport and epithelial function.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3042822-44-3
Applications	ENaC Inhibitor
Formula	C₂₄H₃₆ClN₇O₉P₂
Molecular Weight	663.98
SMILES	ClC1=CN=C(N)C(C(NCC2=[N+](CC)C(C=CC(OCC(NCCOCP(C)(C)=O)=O)=C3)=C3N2CC)=O)=N1.[O-]P(O)(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.