BI-1347
Catalog No.: A18769
CDK8 inhibitor
BI-1347 is a selective inhibitor of CDK8/cyclin C with an IC50 of 1.1 nM.
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Biological Activity
| Description | BI-1347 is a selective inhibitor of CDK8/cyclin C with an IC50 of 1.1 nM. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A18769 |
|---|---|
| Formula | C22H20N4O |
| Molecular Weight | 356.43 |
| CAS Number | 2163056-91-3 |
| SMILES | O=C(N(C)C)CN1N=CC(C2=CC=C(C3=CN=CC4=C3C=CC=C4)C=C2)=C1 |
| Synonyms | BI-1347; BI1347; BI 1347 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro | DMSO | 70 mg/mL (196.39 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (8.41 mM) | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.06 mL | 140.28 mL | 280.56 mL |
| 0.5 mM | 5.61 mL | 28.06 mL | 56.11 mL |
| 1 mM | 2.81 mL | 14.03 mL | 28.06 mL |
| 5 mM | 0.56 mL | 2.81 mL | 5.61 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
