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Catalog No.: A18769

CDK8 inhibitor


BI-1347 Chemical Structure

CAS NO. 2163056-91-3

BI-1347 is a selective inhibitor of CDK8/cyclin C with an IC50 of 1.1 nM.

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Biological Activity

BI-1347 is a selective inhibitor of CDK8/cyclin C with an IC50 of 1.1 nM.
In vitro DMSO 70 mg/mL (196.39 mM)
Water Insoluble
Ethanol 3 mg/mL (8.41 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.06 mL 140.28 mL 280.56 mL
0.5 mM 5.61 mL 28.06 mL 56.11 mL
1 mM 2.81 mL 14.03 mL 28.06 mL
5 mM 0.56 mL 2.81 mL 5.61 mL

*The above data is based on the productmolecular weight 356.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18769
Actions Inhibitor
CAS No. 2163056-91-3
Formula C22H20N4O
M. Wt 356.43
Purity >98%
Synonyms BI-1347; BI1347; BI 1347

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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