BI-3231 is a potent and selective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating IC50 values of 1 nM and 13 nM for human and mouse HSD17B13, respectively. This compound is valuable for research into nonalcoholic steatohepatitis (NASH) and various liver disorders, facilitating the investigation of HSD17B13's role in lipid metabolism and liver function. Its selective inhibition offers a promising avenue for understanding and potentially treating these conditions.
BI-3231 is a potent and selective inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13), demonstrating IC50 values of 1 nM and 13 nM for human and mouse HSD17B13, respectively. This compound is valuable for research into nonalcoholic steatohepatitis (NASH) and various liver disorders, facilitating the investigation of HSD17B13's role in lipid metabolism and liver function. Its selective inhibition offers a promising avenue for understanding and potentially treating these conditions.
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