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BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18 mL | 90 mL | 180 mL |
| 0.5 mM | 3.6 mL | 18 mL | 36 mL |
| 1 mM | 1.8 mL | 9 mL | 18 mL |
| 5 mM | 0.36 mL | 1.8 mL | 3.6 mL |
*The above data is based on the productmolecular weight 555.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18894 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 555.55 |
| Formula | C28H28F3N5O4 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1227948-02-8 |
| Synonyms | BI 4464, BI4464 |
| SMILES | O=C(NC1CCN(C)CC1)C2=CC=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CC5)=C4C5=O)=N3)C(OC)=C2 |
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