Signaling Pathway
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| Discription | BI-4464 is a highly selective ATP competitive inhibitor of PTK2/FAK, with an IC50 of 17 nM. A PTK2 ligand for PROTAC. |
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| Catalog Num | A18894 |
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| Formula | C28H28F3N5O4 |
| Molecular Weight | 555.55 |
| CAS Number | 1227948-02-8 |
| SMILES | O=C(NC1CCN(C)CC1)C2=CC=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CC5)=C4C5=O)=N3)C(OC)=C2 |
| Synonyms | BI 4464, BI4464 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 23 mg/mL (41.4 mM) | |
| Water | Insoluble | ||
| Ethanol | 12 mg/mL (21.6 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18 mL | 90 mL | 180 mL |
| 0.5 mM | 3.6 mL | 18 mL | 36 mL |
| 1 mM | 1.8 mL | 9 mL | 18 mL |
| 5 mM | 0.36 mL | 1.8 mL | 3.6 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
