Documents & Downloads

BI-8668

ENaC Inhibitor

BI-8668 is a selective inhibitor of the epithelial sodium channel (ENaC), primarily involved in regulating sodium and fluid balance in epithelial tissues. This compound has demonstrated significant potential in the study of cystic fibrosis, a genetic disorder affecting respiratory and digestive systems. BI-8668 serves as a valuable tool for elucidating mechanisms of ENaC modulation and evaluating therapeutic strategies for cystic fibrosis management.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2084059-97-0
Applications	ENaC Inhibitor
Formula	C₂₃H₃₂Cl₂N₈O₂
Molecular Weight	523.46
SMILES	O=C(C1=NC(Cl)=CN=C1N)NCC2=[N+](CC)C3=C(C=CC(C(N(CCN(C)C)C)=O)=C3)N2CC.[Cl-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.