Fig. 1 · Structure
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BI 99179
FAS Inhibitor
BI 99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an IC50 of 79 nM. It serves as a valuable chemical probe for studying lipid metabolism-related diseases, enabling in vivo validation of FAS as a therapeutic target. Following oral administration in rats, BI 99179 demonstrates significant exposure in both peripheral and central tissues, supporting its utility in pharmacological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1291779-76-4 |
| Applications | FAS Inhibitor |
| Formula | C23H25N3O3 |
| Molecular Weight | 391.46 |
| SMILES | O=C([C@H]1C[C@@H](NC(CC)=O)CC1)N(C2=CC=C(C3=NC4=CC=CC=C4O3)C=C2)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.