Bibf1120 (Nintedanib)

BIBF1120 (Vargatef) is a novel triple angiokinase inhibitor that inhibits three growth factor receptors simultaneously: VEGFR, PDGF and FGFR.
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Product Name Price Stock Qty
Bibf1120 5mg
Special Price $32.00 Regular Price $40.00
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Bibf1120 10mg
Special Price $48.00 Regular Price $60.00
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Bibf1120 50mg
Special Price $80.00 Regular Price $100.00
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Bibf1120 100mg
Special Price $120.00 Regular Price $150.00
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Adooq Products cited in reputable paper
Adooq's Bibf1120 (Nintedanib) has been cited by 2 publications
  • Majid Momeny, .et al. , Life Sci, 2021, Dec 15;287:120100 PMID: 34715143
  • Chun-Jung Chang, .et al. , Biochem Pharmacol, 2021, Jan;183:114356 PMID: 33285108
  • Biological Activity
    Discription BIBF1120 (Vargatef) is a novel triple angiokinase inhibitor that inhibits three growth factor receptors simultaneously: VEGFR, PDGF and FGFR.
    Targets
    Target Value
    Product Information
    Catalog Num A10137
    Formula C31H33N5O4
    Molecular Weight 539.6
    CAS Number 928326-83-4, 656247-17-5
    SMILES CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N/C(=C\3/C4=C(C=C(C=C4)C(=O)OC)NC3=O)/C5=CC=CC=C5
    Synonyms Vargatef
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 6 mg/mL (11.11 mM)
    Water Insoluble
    Ethanol 3 mg/mL (5.55 mM)
    In vivo 5% DMSO+40% PEG 300+2% Tween 80+ddH2O 0.23 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 18.53 mL 92.66 mL 185.32 mL
    0.5 mM 3.71 mL 18.53 mL 37.06 mL
    1 mM 1.85 mL 9.27 mL 18.53 mL
    5 mM 0.37 mL 1.85 mL 3.71 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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