Fig. 1 · Structure
Documents & Downloads
BIBW 22
Tumor modulator
BIBW 22 is a dipyridamole analogue that functions as a bifunctional modulator targeting P-glycoprotein and nucleoside transport in tumor cells. Its potent activity makes it valuable for research in cancer biology, particularly in understanding drug resistance mechanisms and nucleoside transport dynamics in tumor environments. BIBW 22 can be utilized in studies focused on enhancing the efficacy of chemotherapeutic agents.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 137694-16-7 |
| Applications | Tumor modulator |
| Formula | C30H43N7O4 |
| Molecular Weight | 565.71 |
| Synonyms | BIBW22BS |
| SMILES | CC(C)(CN(CCO)C1=C2N=C(C(N3C[C@@H](O[C@@H](C3)C)C)=NC2=NC(N4C[C@@H](O[C@@H](C4)C)C)=N1)C5=CC=CC=C5)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.