Fig. 1 · Structure
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BIM5078
HNF4α Antagonist
BIM5078 is an antagonist of hepatocyte nuclear factor 4α (HNF4α), which effectively inhibits the expression of target genes regulated by HNF4α. This compound has been shown to repress insulin promoter activity, making it a valuable tool for studying the roles of HNF4α in metabolic disorders. BIM5078 is utilized in research focusing on cancer and diabetes, contributing to the understanding of these diseases at a molecular level.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 337506-43-1 |
| Applications | HNF4α Antagonist |
| Formula | C14H10ClN3O4S |
| Molecular Weight | 351.76 |
| SMILES | [O-][N+](C1=CC=C(C(S(=O)(N2C3=C(N=C2C)C=CC=C3)=O)=C1)Cl)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.