Fig. 1 · Structure
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Bimosiamose disodium
Pan-Selectin Inhibitor
Bimosiamose disodium is a potent pan-selectin inhibitor, effectively targeting E-selectin, P-selectin, and L-selectin with IC50 values of 88 μM, 20 μM, and 86 μM, respectively. This compound demonstrates significant anti-inflammatory activity, making it a valuable tool for investigating inflammatory processes and selectin-mediated interactions in various biological contexts. Its application in research may provide insights into the mechanisms of diseases associated with selectin function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 187269-60-9 |
| Applications | Pan-Selectin Inhibitor |
| Formula | C46H52Na2O16 |
| Molecular Weight | 906.88 |
| Synonyms | TBC-1269Z |
| SMILES | OC[C@H]([C@@H](O)[C@H](O)[C@@H]1O)O[C@@H]1OC(C=C2)=C(C3=CC(CC(O[Na])=O)=CC=C3)C=C2CCCCCCC(C=C4)=CC(C5=CC(CC(O[Na])=O)=CC=C5)=C4O[C@H]6O[C@@H]([C@@H](O)[C@H](O)[C@@H]6O)CO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.